Estrogen Detoxification - Detoxify To Prevent
Potential Health Problems
play an important role in bone formation and maintenance. They exert
protective effects on the heart and influence behavior and mood.
You MUST DETOXIFY ESTROGEN to prevent potential health problems
such as breast or prostate cancer.
Estrogens circulate around the body bound to other proteins called
sex hormone binding globulins (SHBG). Only unbound estrogens can
enter target-tissue cells and induce biological activity - some
good, some bad. So, any changes in these proteins (SHBG's) will
alter estrogen metabolism.
The ultimate effect of estrogen depends on how it is metabolized.
Metabolism takes place primarily in the liver through detoxification
that includes hydroxylation, methylation, glucoronidation, sulfation,
and ends with excretion in the urine and feces.
There are 3 different pathways which estrogen can be metabolized
within the liver. Only one is a healthy, happy choice. The other
two cause cardiovascular issues and cancer. Unfortunately, there
are many environmental and dietary reasons that push the detoxification
down the wrong pathways. Many adult bodies do not detoxify properly
- often because of dietary insufficiency and environmental overload
of toxins and stresses. For some, the problem lies in the methylation,
or failure to methylate properly, for others, glucoronidation and
sulfation. If it's not the healthy pathway, you are setting up your
body for future cardiovascular disease or cancer.
What Happens When Estrogen Goes Down The Wrong
- Estrogens are recycled rather than excreted. Without proper
metabolism, excess estrogens are created. This can lead to cancer
in hormone sensitive tissue, such as breast or prostate.
- Your body will produce high levels of quinones - which have
potential carcinogenic effects.
- Your body will store estrogens in target tissues, primarily
the breast and prostate - with the ultimate potential - development
of breast and prostate cancer. FACT: women who send estrogen
down the wrong pathway have significantly elevated risk of breast
What Would Cause Your Body To Send Estrogen Down The Wrong Pathway?
Rx - WHAT YOU CAN DO
Unbalanced intestinal bacteria - excess bad
guys allow estrogen to recycle and prevent them from being
Maintain proper intestinal health through
diet and supplement with NCFM strain probiotics and Calcium
Most adults do not methylate properly.
Check your homocysteine level, support methylation
with the proper nutrients including B complex, SAM and Magnesium.
Numerous pesticides and carcinogens, certain
drugs (cyclosporin, cimetidine (Tagamet), being very overweight,
and genetics promote an unhealthy pathway.
Dietary modifications to reduce pesticide
and carcinogen exposure - including adding more soy, flax,
kudzu and cruciferous veggies will help promote the correct
pathway. Eat organic only and clean them well!
|Excess insulin in the bloodstream prompts the
ovaries to reduce SHBG - the binding proteins, thus increasing
levels of free estrogens - which can float around and enter
||Limit your intake of refined carbohydrates. You
may add Conjugated Linoleic Acid to help control insulin and
blood sugar levels. Add more foods high in fiber, phytoestrogens,
lignans and flavonoids. For example, soy, flax, alfalfa, and
all green veggies, including green tea.
Relief is available!! You do not have to live with uncomfortable
PMS, menopause flashes, backaches, joint, and muscle pain, feelings
of depression, bloating, swelling, or even weight gain. Clean up
your diet, and detoxify your body by including high amounts of flaxseed,
soy and kudzu, along with B complex vitamins. Eliminate any environmental
estrogens and pollutants Pesticides found on produce, sodium lauryl
sulfate and other chemicals in hair and body care products should
be eliminated and switched out for healthier, non chemical laden
products. Those pollutants found in air are challenging to eliminate,
but use of air filters in the home can help. Use the following guidelines
when making dietary choices:
- Fiber: Eat adequate fiber every day. Fiber can bind to
estrogen and prevent re-circulation. Fiber also influences healthy
- Fats: A proper balance among types and amount of dietary
fats can prevent cancer. Breast cancer cells exposed to EPA (omega
3 fatty acids) promotes detoxification down the correct pathway.
- Protein: Inadequate protein may prevent adequate SHBG
to bind the estrogens, and additional negative complications.
Take action now. DO NOT wait, particularly if you have a
family history of breast or prostate cancer. You can prevent these
debilitating and devastating diseases.
Eltman, MPH, RD