Sugar Substitutes - Acesulfame Potassium Artificial Sweeteners To Save Calories

Acesulfame potassium is a calorie-free artificial sweetener, also known as Acesulfame K or Ace K, and marketed under the trade names Sunett and Sweet One. In the European Union it is also known under the E number (additive code) E950. It was discovered accidentally in 1967 at Hoechst AG (now Sanofi-Aventis.)

Chemically, acesulfame potassium is the potassium salt of 6-methyl-1,2,3- oxathiazine-4(3H)-one 2,2-dioxide. It is white crystalline powder with molecular formula of C4H4NO4KS and molecular weight of 201.24.

Acesulfame K is 100-200 times sweeter than sucrose (table sugar), or about half as sweet as aspartame or saccharin. Like saccharin, it has a slightly bitter aftertaste, especially at high concentrations. Kraft Foods has patented the use of sodium ferulate to mask acesulfame's aftertaste. Alternatively, acesulfame K is often blended with aspartame or other sweeteners. These blends are reputed to give a more sugar-like taste where each sweetener masks the other's aftertaste, and to exhibit a synergistic effect wherein the blend is sweeter than its components.

Unlike aspartame, it is stable under heat, even under moderately acidic or basic conditions, allowing it to be used in baking, or in products that require a long shelf life.

Popular products containing acesulfame K include Diet Rite Cola, Pepsi Max, Coca-Cola Zero, Fresca, Diet Coke with Splenda, Trident gum, Wrigley's Spearmint gum, some SoBe products and sugarfree Jell-O. In carbonated drinks it is almost always used in conjunction with another sweetener, such as aspartame or sucralose.

Safety
Acesulfame K has been approved for use in foods in Europe since 1983, in the United States since 1988, and in Canada since 1994. In 1985, the European Union's Scientific Committee for Food published a comprehensive assessment of sweetening agents. This committee of toxicological experts from the EU member countries accepted Acesulfame K for use in foods and beverages. Safety of usage of Acesulfame K has also been examined by JECFA, with the conclusion that Acesulfame K is safe to use, at least at levels less than the acceptable daily intake of 15 mg/kg of body weight.

However, the studies that purport to show safety have been challenged by a number of individuals and organizations, most notably the Center for Science in the Public Interest in the USA. They claim that the existing studies are inadequate (despite being peer-reviewed), that there are flaws in the research protocols, dosing, and time length of the studies, and that as a result the carcinogenicity of acesulfame K may not be properly understood. In particular they note that there have not been long-term human studies, so they doubt the studies which show that acesulfame is rapidly absorbed and then excreted unchanged (i.e., not metabolized by the human body) are representative of the long-term.

The EU's Scientific Committee in its re-evaluation of the product following concerns from CSPI and others concluded that Acesulfame K is not harmful, as no reproducible mutagenic effects have been discovered in years of use, noting [1]:

"The Committee considered that although the carcinogenicity studies are old they could still be used in the safety evaluation of acesulfame K. Moreover, the Committee does not agree with the interpretation of the CSPI that there is an indication of possible carcinogenicity from these studies. The one aberrant, positive mutagenicity finding in mouse bone marrow cells could not be replicated and all other mutagenicity findings were negative. No other new data has appeared indicating potential harmful effects. Thus there is no reason to require any additional studies of chronic toxicity/carcinogenicity or mutagenicity."

Currently, the scientific community's official position is that acesulfame K is safe to consume, which is the view put forth on the sweetener industry's public relations website, IFIC. IFIC glosses over the manufacture of acesulfame potassium, stating it is made from acetoacetic acid, while ignoring its other reactants, possibly sulfuric acid and ammonia.

An elevation in insulin levels is known to cause an increase in cravings for food and consequently, weight gain. Sodium saccharin, sodium cyclamate, stevioside and acesulfame-K are all known to enhance insulin release even though they are not carbohydrates.

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Artificial Sugar Substitutes

Information Provided by Wikipedia

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